DAG

Rolf Groenwold is a professor of Clinical Epidemiology, with a focus on methods for research of medical treatments, at the departments of Clinical Epidemiology and of Biomedical Data Sciences of the LUMC. Together with his research group, he focuses on the development, improvement, and evaluation of methods for observational studies of medical treatments.

Since the start of his research career, Rolf has focused on methods for observational studies of medical treatments. In 2012, he received a VENI research grant and in 2016 a VIDI research grant from the Dutch Research Council (ZonMW). Where the VENI project dealt with statistical methods for dealing with incomparability of treatment groups in medical research (i.e., confounding), the VIDI project extended this work and aimed for developing statistical methods that jointly address different sources of bias in medical research using routinely collected health data (notably, bias due to incomparability, bias due to missing data, and bias due to measurement error). Following the receipt of a personal research fellowship from the Leiden University Medical Centre (LUMC), this work could be extended to focus on methods needed for studies using routinely collected health data (or electronic health records data).

Rolf combines his research into epidemiological methods with many collaborations on various clinical topics.

An overview of his research activities can be found at his ORCID profile


Recent and ongoing projects (selection)

2022 - ongoing GetReal Institute 'The persuasiveness of real-world evidence: a multi-faceted approach'
2017-2022 ZonMW Vidi 'Optimizing the methodological framework for studies of the effects of medical interventions using routine care data'
2018-2021 LUMC fellowship
2012-2015 ZonMW Veni 'Evaluating the effects of medical treatments using clinical data: observational comparative effectiveness research'

Supervised PhD dissertations

Luijken

K. Luijken (2022)
The impact of epidemiologic methods on findings in studies of causal effects and prediction modelling
Promotor: Prof. dr. R.H.H. Groenwold

Penning de Vries

B.B.L. Penning de Vries (2022)
Methodological Obstacles in Causal Inference: Confounding, Missing Data, and Measurement Error
Promotor: Prof. dr. R.H.H. Groenwold
Co-promotor: dr. M. van Smeden

Peek

J. Peek (2021)
Traumatic Rib Fractures - Epidemiology, Treatment and Outcome
Promotors: Prof. dr. L.P.H. Leenen, Prof. dr. R.H.H. Groenwold
Co-promotors: dr. R.M. Houwert, dr. D. van der Velde

Ochen

Y. Ochen (2021)
Challenges and opportunities in Trauma research
Promotor: Prof. dr. R.H.H. Groenwold
Co-promotors: dr. R.M. Houwert, dr. R.B. Beks

Beks

R.B. Beks (2019)
Defining the value of observational studies in trauma
Promotors: Prof. dr. L.P.H. Leenen, Prof. dr. R.H.H. Groenwold
Co-promotors: dr. R.M. Houwert, dr. D. van der Velde

Althunian

T.A. Althunian (2019)
Non-inferiority studies: a methodological and regulatory perspective
Promotors: Prof. dr. A. de Boer, Prof. dr. O. H. Klungel, Prof. dr. R. H. H. Groenwold

Pajouheshnia

R. Pajouheshnia (2018)
Prognostic research in treated populations
Promotor: Prof. dr. K.G.M. Moons
Copromotors: Dr. R.H.H. Groenwold, Dr. L.M. Slingerland-Peelen

Brakenhoff

T.B. Brakenhoff (2018)
Confounding and measurement error correction in epidemiological research
Promotor: Prof. dr. K.G.M. Moons
Copromotor: Dr. R.H.H. Groenwold

Hazelbag

C.M. Hazelbag (2016)
Methods for time-varying exposures
Promotors: Prof. dr. A.W. Hoes
Co-promotor: Dr. R.H.H. Groenwold

Rietbergen

C. Rietbergen (2016)
Quantitative Evidence Synthesis with Power Priors
Promotors: Prof. dr. H. Hoijtink, Prof. dr. K.G.M. Moons
Co-promotors: Dr. I. Klugkist, Dr. R.H.H. Groenwold

Jonkman

N.H. Jonkman (2016)
Self-management interventions for patients with a chronic disease: what works and in whom?
Promotors: Prof. dr. M.J. Schuurmans, Prof. dr. A.W Hoes
Co-promotors: Dr. J.C.A. Trappenburg, Dr. R.H.H. Groenwold

Uddin

M.J. Uddin (2014)
Performance of statistical methods to control for unmeasured confounding in pharmacoepidemiology
Promotors: Prof. dr. A. de Boer, Prof. dr K.C.B. Roes
Co-promotor: Dr. R.H.H. Groenwold, Dr. O.H. Klungel

Schmidt

A.F. Schmidt (2014)
Effect Modification of Interventions
Promotors: Prof. dr. A.W. Hoes, Prof. dr. M. Nielen
Co-promotors: Dr. R.H.H. Groenwold, Dr. O.H. Klungel

Ali

M.S. Ali (2014)
Improving propensity score methods in pharmacoepidemiology
Promotors: Prof. dr. A. de Boer, Prof. dr. A.W. Hoes
Co-promotor: Dr. O.H. Klungel, Dr. R.H.H. Groenwold

Siregar

S. Siregar (2013)
Safety in cardiac surgery (cum laude)
Promotors: Prof. dr. L.A. van Herwerden, Prof. dr Y. van der Graaf
Co-promotor: Dr. R.H.H. Groenwold

Boessen

R. Boessen (2013)
Methods to improve the efficiency of confirmatory clinical trials
Promotors: Prof. dr. D.E. Grobbee, Prof. dr. K.C.B. Roes
Co-promotors: Dr. M.J. Knol, Dr. R.H.H. Groenwold

Schuit

E. Schuit (2013)
Risk-based management in obstetrics
Promotors: Prof. dr. K.G.M. Moons, Prof. dr. B.W.J. Mol
Co-promotors: Dr. A. Kwee, Dr. R.H.H. Groenwold